ABSTRACT
Background: Patients frequently need a rapid sequenceinduction (RSI) endotracheal intubation technique duringemergencies or electively to protect against aspiration inconditions like pregnancy, abdominal pathologies especiallyobstruction or ileus, neurologic disease, or in difficult airway.Traditionally succinylcholine has been the most commonlyused muscle relaxant for this purpose because of its fast onsetand short duration; unfortunately, it can have serious sideeffects. Rocuronium has been suggested as an alternative tosuccinylcholine for intubation.Methods: This study was done at department of anesthesiaSMBT Institute of Medical Science and Research Center,Dhamangaon Tal. Igatpuri, Nashik, Maharashtra, India. Thepatients were systematically randomized into three groups oftwenty each. Group A: Succinylcholine 1.5 mg/kg, Group B:Rocuronium bromide 0.6 mg/kg &Group C: Rocuroniumbromide 0.9 mg/kg.Intubating conditions, onset of action andadverse effects were observed.Results: It was observed that group A & group C patients hadexcellent intubation conditions with faster onset of action forgroup A patients. Adverse effects were not seen in any of thethree groups.Conclusion: Our study concludes that Succinylcholine is anideal agent for intubation in all surgical procedures. Intubatingconditions of Rocuronium bromide at a dose of 0.9mg/kg(3xED95) is comparable to Succinylcholine 1.5mg/kgat1minute. Rocuronium bromide 0.9mg/kg can be used safelyin patients where succinylcholine is contraindicated.
ABSTRACT
Background: Motor Vehicle crashes are a remarkable reasonfor casualty all over throughout the world. By 2020, enginevehicle damage is predictable to wind up noticeably the thirddriving supporter of the international weight of illness on theglobe.Methods: The study was conducted for the period of one yearand One hundred subjects were studied at Department ofForensic Medicine &Toxicology S.N. Medical College Jodhpur.Subsequent information was collected from the study: Type ofInjuries (Grievous or Non grievous), Alcohol intake present orabsent, Number of Abrasions/ Bruises/Lacerations andGlasgow Coma Scale. Data was collected and tabulated.Statistical analysis was done. For quantitative data ‘t’ test wasused and for qualitative chi-square test was used. The ‘p’ value<0.05 is considered as statistically significant.Results: Out of total 100 patients, 55 helmeted and 35 nonhelmeted individuals, 22 and 23 persons sustained grievousinjuries respectively. In case of helmeted individuals, thepresence and absence of alcohol intake was observed in 26and 29 cases respectively. Out of 55 helmeted persons 54persons sustained abrasions, 39 had bruises and 17individuals had lacerations. The Glasgow Coma Scale (GCS)score between 3-7 and 8-15 of helmeted individuals were 20%and 80% of the individuals respectively.Conclusions: Serious injury has been found more in nonhelmeted individuals in comparison to helmeted individuals.Alcohol intake has been found more in helmeted individuals incomparison to non-helmeted individuals. The most commoninjury in helmeted individuals has been found to be abrasion.Lacerations have been found more in non-helmetedindividuals. GCS of less than 7 was found to be in more in nonhelmeted individuals in comparison to the helmeted individuals
ABSTRACT
Background: Postoperative sore throat (POST) is a slightcomplication after general anaesthesia. Numerous agents havebeen used as lubricant to lessen the incidence of POST withvariable efficacy.Methods: We compare the incidence of POST with 0.05%betamethasone gel and 2% lignocaine jelly as a lubricant forLMA insertion in patients undergoing general anaesthesia.Sixty subjects were separated randomly into two groups.Patients in Group B (n = 30) had 2.5 ml of 0.05% ofbetamethasone gel while the Group L had 2.5 ml of 2%lignocaine jelly applied on the cuff of LMA. After criterioninduction and insertion of LMA cuff inflated to 60 cm of H2Oand was maintained at the same throughout the surgery.Results: In PACU, patients evaluated about sore throat atimmediate and 24 h post-operative period. POST was not seenin any of the patients of Group B. In group L 13% of thepatients had 1st degree and 3% had 2nd degree of sore-throatin immediate post-operative period. After 24 h 3%patients had1st degree sore-throat and 1% patients had 2nd degree ofsore-throat in Group L patients.Conclusion: We conclude that lubricating cuff of LMA with0.05% of betamethasone gel is efficient in reducing theincidence of POST.
ABSTRACT
Background: Intrathecal xylocaine with midazolam is evermore being used for postoperative pain relief. There were littleconcern like respiratory depression and neurotoxicity with theuse of inthrathecal midazolam.Methods: In this study total 90 patients of with 30 patients ineach group using intrathecal drugs for postoperative pain reliefin Lower segment cesarean section. The three groups wereintrathecal xylocaine, intrathecal xylocaine + 1mg midazolamand intrathecal xylocaine + 2 mg midazolam respectively.Results: The demographic and hemodynamic variables werecomparable between the three groups. Only shivering andhypotension was noted with use of midazolam which was nodifferent from other groups.Conclusion: Intrathecal midazolam as an adjuvant tointrathecal xylocaine was not associated with significantadverse events or complications.